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Article

Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jan 2015

Favero F, Joshi T, Marquard A M, Birkbak N J, Krzystanek M, Li Q, Szallasi Z, Eklund A C

Abstract excerpt

BACKGROUND: Exome or whole-genome deep sequencing of tumor DNA along with paired normal DNA can potentially provide a detailed picture of the somatic mutations that characterize the tumor. However, analysis of such sequence data can be complicated by the presence of normal cells in the tumor spec...

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Identifiers

PMID: 25319062
DOI: 10.1093/annonc/mdu479
PMCID: PMC4269342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25319062-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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