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Article

Characterization of AprE176, a fibrinolytic enzyme from Bacillus subtilis HK176.

Journal of microbiology and biotechnology - 1 Jan 2015

Jeong Seon-Ju, Heo Kyeong, Park Ji Yeong, Lee Kang Wook, Park Jae-Yong, Joo Sang Hoon, Kim Jeong Hwan

Abstract excerpt

Bacillus subtilis HK176 with high fibrinolytic activity was isolated from cheonggukjang, a Korean fermented soyfood. A gene, aprE176, encoding the major fibrinolytic enzyme was cloned from B. subtilis HK176 and overexpressed in E. coli BL21(DE3) using plasmid pET26b(+). The specific activity of purified AprE176 was 216.8 ± 5.4 plasmin unit/mg protein and the optimum pH and temperature were pH 8.0 and 40°C,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25315053
DOI: 10.4014/jmb.1409.09087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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