Article
Maturation of Fibrinolytic Bacillopeptidase F Involves both Hetero- and Autocatalytic Processes.
Applied and environmental microbiology - 1 Jan 2016
Meng Dongheng, Dai Meihong, Xu Bi-Lin, Zhao Zhong-Shu, Liang Xiaoliang, Wang Mingqiu, Tang Xiao-Feng, Tang Bing
Abstract excerpt
Bacillopeptidase F (Bpr) is a fibrinolytic serine protease produced by Bacillus subtilis. Its precursor is composed of a signal peptide, an N-terminal propeptide, a catalytic domain, and a long C-terminal extension (CTE). Several active forms of Bpr have been previously reported, but little is known about the maturation of this enzyme. Here, a gene encoding a Bpr (BprL) was cloned from B. subtilis LZW and...
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