Article
The ALDH2 rs671 polymorphism affects post-stroke epilepsy susceptibility and plasma 4-HNE levels.
PloS one - 1 Jan 2014
Yang Heng, Song Zhi, Yang Guo-Ping, Zhang Bi-Kui, Chen Min, Wu Tian, Guo Ren
Abstract excerpt
Recent studies have demonstrated the protective effect of mitochondrial aldehyde dehydrogenase 2 (ALDH2) in cardiovascular diseases. Increased levels of the potential ALDH2 substrate 4-hydroxynonenal (4-HNE) are involved in myocardial/cerebral ischemia accompanied by a high level of oxidative stress. In this investigation, we first performed a case-control study to explore the potential association of ALDH2 rs671...
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