Article
Homozygous ALDH2*2 Is an Independent Risk Factor for Ischemic Stroke in Taiwanese Men.
Stroke - 1 Sept 2016
Sung Yueh-Feng, Lu Chun-Chung, Lee Jiunn-Tay, Hung Yi-Jen, Hu Chaur-Jong, Jeng Jiann-Shing, Chiou Hung-Yi, Peng Giia-Sheun
Abstract excerpt
BACKGROUND AND PURPOSE: The *2 allele of the aldehyde dehydrogenase 2 gene (ALDH2) is the most common variant in Asian populations. The variant resulting in enzyme dysfunction was highly related to coronary artery disease. Recently, genome-wide association studies also discovered that the 12q24 locus near ALDH2 gene was associated with hypertension and ischemic stroke. This study intended to further investigate...
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