Article
Aldehyde dehydrogenase 2 polymorphism as a protective factor for intracranial vascular stenosis in ischemic stroke in Han Chinese.
The International journal of neuroscience - 1 Jan 2016
Qu Yun, Zhang Hui-long, Yu Li-mei, Sun Ying, Wu Hong-liang, Chen Yu-guo
Abstract excerpt
AIM: Aldehyde dehydrogenase 2 (ALDH2) is a key enzyme that metabolizes acetaldehyde to acetic acid. ALDH2 gene polymorphism modifies its activity and the mutation of ALDH2 gene has been reported to be associated with the protection against ischemic stroke. However, the potential association of allelic variation of ALDH2 with intracranial vascular stenosis and the clinical characteristics of ischemic stroke...
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