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Article

Extreme high prevalence of a defective mannose-binding lectin (MBL2) genotype in native South American West Andean populations.

PloS one - 1 Jan 2014

Sandoval José Raul, Madsen Hans O, De Stefano Gianfranco, Descailleaux-Dulanto Jaime, Velazquez-Reinoso Margarita, Ñique Cesar, Fujita Ricardo, Garred Peter

Abstract excerpt

Mannose-binding lectin (MBL) is one of the five recognition molecules in the lectin complement pathway. Common variant alleles in the promoter and structural regions of the human MBL gene (MBL2) influence the stability and serum concentration of the protein. Epidemiological studies have shown tha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25313559
DOI: 10.1371/journal.pone.0108943
PMCID: PMC4196846

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25313559-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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