Article
Modulating effects of WT1 on interferon-β-vitamin D association in MS.
Acta neurologica Scandinavica - 1 Apr 2015
Lin R, Taylor B V, Charlesworth J, van der Mei I, Blizzard L, Stewart N, Ponsonby A-L, Dwyer T, Pittas F, Simpson S
Abstract excerpt
OBJECTIVE: To investigate whether those genes involved in the vitamin D pathway modulate the relationship between 25-hydroxyvitamin D (25(OH)D) and IFN-β, the relationship between IFN-β and sun in predicting 25(OH)D, and the interaction between IFN-β and 25(OH)D in modulating relapse risk in patients with MS. METHODS: Prospective cohort study of 169 participants with MS and genotype data followed 2002-2005....
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