Article

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity

2020-07-26

Abstract excerpt

<h4>Background</h4> Multiple sclerosis (MS) disease risk is associated with reduced sun exposure. This study assessed the relationship between measures of sun-exposure (vitamin D (vitD), latitude) and MS disease severity, the mechanisms of action, and effect-modification by medication and sun-sensitivity associated MC1R variants. <h4>Methods</h4> Two multi-center cohort studies (n NationMS =946, n BIONAT =99...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 45f49ec6-be0f-5700-ae42-c48531e3771b
DOI: 10.1101/2020.07.20.20157800

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severityDOI 10.1101/2020.07.20.20157800Read

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.Semantic proximity Read

Epstein-Barr Virus, Lower Vitamin D, Low Sun Exposure, and HLA-DRB1*1501 Risk Variant Share Common Epigenetic Pathways Leading to Multiple Sclerosis Onset.Semantic proximity Read

Environmental triggers of multiple sclerosisSemantic proximity Read

Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent MS riskSemantic proximity Read

Linking Mechanisms of Vitamin D Signaling with Multiple SclerosisSemantic proximity Read

Multiple sclerosis, vitamin D, and HLA-DRB1*15.Semantic proximity Read

Epigenetic research in multiple sclerosis: progress, challenges, and opportunitiesSemantic proximity Read

MS Sunshine Study: Sun Exposure But Not Vitamin D Is Associated with Multiple Sclerosis Risk in Blacks and Hispanics.Semantic proximity Read

Short-term changes in frequencies of circulating leukocytes associated with narrowband UVB phototherapy in people with clinically isolated syndromeSemantic proximity Read

Modulating effects of WT1 on interferon-β-vitamin D association in MS.Semantic proximity Read

Genomic binding sites and biological effects of the vitamin D--VDR complex in multiple sclerosis [corrected].Semantic proximity Read

Multiple Sclerosis: Lipids, Lymphocytes, and Vitamin DSemantic proximity Read