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Article

Smoking affects the interferon beta treatment response in multiple sclerosis.

Neurology - 13 Feb 2018

Petersen Eva R, Oturai Annette B, Koch-Henriksen Nils, Magyari Melinda, Sørensen Per S, Sellebjerg Finn, Søndergaard Helle B

Abstract excerpt

OBJECTIVE: To investigate whether smoking in patients with relapsing-remitting multiple sclerosis (RRMS) treated with interferon beta (IFN-β) is associated with the relapse rate and whether there is an interaction between smoking and human leukocyte antigen (HLA)-DRB1*15:01, HLA-A*02:01, and the N-acetyltransferase-1 (NAT1) variant rs7388368A. METHODS: DNA from 834 IFN-β-treated patients with RRMS from the Danish...

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Share to Arylamine N-Acetyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29343473
DOI: 10.1212/WNL.0000000000004949

Genes

NAT1

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