Article
Vitamin D related genetic polymorphisms affect serological response to high-dose vitamin D supplementation in multiple sclerosis.
PloS one - 1 Jan 2021
Mimpen Max, Rolf Linda, Poelmans Geert, van den Ouweland Jody, Hupperts Raymond, Damoiseaux Jan, Smolders Joost
Abstract excerpt
INTRODUCTION: A poor 25-hydroxyvitamin D (25(OH)D) status is a much replicated risk factor for developing multiple sclerosis (MS), and several vitamin D-associated single nucleotide polymorphisms (SNPs) have been associated with a higher risk of MS. However, studies on the benefit of vitamin D supplementation in MS show inconclusive results. Here, we explore whether vitamin D-associated SNPs and MS risk alleles...
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