Article
Stimulated PBMC-produced IFN-γ and TNF-α are associated with altered relapse risk in multiple sclerosis: results from a prospective cohort study.
Journal of neurology, neurosurgery, and psychiatry - 1 Feb 2015
Simpson Steve, Stewart Niall, van der Mei Ingrid, Otahal Petr, Charlesworth Jac, Ponsonby Anne-Louise, Blizzard Leigh, Dwyer Terence, Pittas Fotini, Gies Peter, Taylor Bruce
Abstract excerpt
BACKGROUND: Altered reactivity of peripheral blood mononuclear cells (PBMC) and their production of cytokines may affect multiple sclerosis (MS) clinical course. We assessed the relationship of stimulated PBMC-produced IFN-γ, TNF-α, IL-4 and IL-10 in modulating relapse risk using a prospective co...
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