Article
The Multiple Sclerosis Severity Score: associations with MC1R single nucleotide polymorphisms and host response to ultraviolet radiation.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Sept 2010
Strange Richard C, Ramachandran Sudarshan, Zeegers Maurice P, Emes Richard D, Abraham Roby, Raveendran Vythilingam, Boggild Mike, Gilford Janice, Hawkins Clive P
Abstract excerpt
BACKGROUND: Multiple sclerosis outcome may be influenced by ultraviolet radiation and vitamin D synthesis, suggesting skin type and genes determining this phenotype are candidates for disability. However, though associations between melanocortin 1 receptor (MC1R) single nucleotide polymorphisms and disability are reported, some data are incompatible with their expected influence on skin type. OBJECTIVE: Determine...
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