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Article

Deletion of interleukin-6 prevents cardiac inflammation, fibrosis and dysfunction without affecting blood pressure in angiotensin II-high salt-induced hypertension.

Journal of hypertension - 1 Jan 2015

González Germán E, Rhaleb Nour-Eddine, D'Ambrosio Martin A, Nakagawa Pablo, Liu Yunhe, Leung Pablo, Dai Xiangguo, Yang Xiao-Ping, Peterson Edward L, Carretero Oscar A

Abstract excerpt

OBJECTIVE: Inflammation has been proposed as a key component in the development of hypertension and cardiac remodeling associated with different cardiovascular diseases. However, the role of the proinflammatory cytokine interleukin-6 in the chronic stage of hypertension is not well defined. Here,...

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Identifiers

PMID: 25304471
DOI: 10.1097/HJH.0000000000000358
PMCID: PMC4256143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25304471-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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