Article
Comprehensive phenotyping of salt-induced hypertensive heart disease in living mice using cardiac magnetic resonance.
European radiology - 1 Feb 2013
Cochet Hubert, Lefrançois William, Montaudon Michel, Laurent François, Pourtau Line, Miraux Sylvain, Parzy Elodie, Franconi Jean-Michel, Thiaudière Eric
Abstract excerpt
OBJECTIVES: To characterise the effects of high-salt diet (HSD) on left ventricular (LV) mass, systolic function and coronary reserve in living mice using cardiac magnetic resonance imaging (MRI). METHODS: Thirty C57BL/6 1-month-old female mice were fed either a control (n = 15) or an HSD (n = 15). After 3 months, LV volumes, ejection fraction and mass were assessed using time-resolved three-dimensional (3D)...
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