Article

Therapeutic Targeting of Interleukin-11 Up-Regulated Angiotensin II Induced Atrial Fibrosis in Mice

2022-06-01

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold> Inflammatory cytokines are closely associated with developing cardiac fibrosis. This research aimed to explore the significant role of IL-11 in atrial fibrosis progression and potential therapeutic targets. <bold>Methods</bold> 367 subjects were included in the case-control study. Blood samples were analyzed for the level of IL-11 by enzyme-linked immunosorbent assa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3205dfaf-d125-567f-a204-e0c9bb49205c
DOI: 10.21203/rs.3.rs-1691037/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Therapeutic Targeting of Interleukin-11 Up-Regulated Angiotensin II Induced Atrial Fibrosis in MiceDOI 10.21203/rs.3.rs-1691037/v1Read

IL-11 is a therapeutic target in idiopathic pulmonary fibrosisSemantic proximity Read

Cardiomyocyte-restricted expression of IL11 causes cardiac fibrosis, inflammation, and dysfunctionSemantic proximity Read

Crosstalk between Atrial Cardiomyocytes and Epicardial Adipose Tissue in Atrial Fibrillation: Insights from Machine Learning Methods and Rat Atrial Fibrillation ModelSemantic proximity Read

Inhibitory effect of microRNA-21 on pathways and mechanisms involved in cardiac fibrosis developmentSemantic proximity Read

LncRNA CFAR promotes cardiac fibrosis via the miR-449a-5p/LOXL3/mTOR axisSemantic proximity Read

Repurposing Nintedanib for Pathological Cardiac Remodeling and DysfunctionSemantic proximity Read

Interleukin 11 therapy causes acute heart failure and its use in patients should be reconsideredSemantic proximity Read

Inflammatory Activation, Epigenetic Signature and Morpho-structural Alteration in a Cohort of Patients With Chronic Heart Failure and Permanent Non-valvular Atrial Fibrillation: A Cross-sectional StudySemantic proximity Read

Atrial Matrix Remodeling in Atrial Fibrillation Patients with Aortic StenosisSemantic proximity Read

IL-1β enhances susceptibility to atrial fibrillation in mice by acting through resident macrophages and promoting caspase-1 expressionSemantic proximity Read

MicroRNA-410-5p exacerbates high-fat diet-induced cardiac remodeling in mice in an endocrine fashionSemantic proximity Read

Prostaglandin I2 signaling prevents angiotensin II-induced atrial remodeling and vulnerability to atrial fibrillation in miceSemantic proximity Read