Article
No evidence of association between variant rs2075650 in lipid metabolism-related locus APOE/TOMM40 and advanced age-related macular degeneration in Han Chinese population.
Experimental biology and medicine (Maywood, N.J.) - 1 Feb 2015
Kan Mengyuan, Weng Xiaoling, Wang Ting, Liu Fatao, Ye Junyi, Zhang Hong, Xu Mingqing, Zhou Daizhan, He Lin, Liu Yun
Abstract excerpt
Age-related macular degeneration (AMD) is a late-onset, neurodegenerative disease. Genes related to lipid metabolism are important in AMD pathogenesis. Recently, a variant rs2075650 located in lipid metabolism-related locus APOE/TOMM40 was identified to be associated with advanced AMD and early AMD, respectively, in two genome-wide association studies with European ancestry, while no association study between...
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