Article
Apolipoprotein E gene and age-related macular degeneration in a Chinese population.
Molecular vision - 20 Apr 2011
Sun Erdan, Lim Apiradee, Liu Xipu, Snellingen Torkel, Wang Ningli, Liu Ningpu
Abstract excerpt
PURPOSE: To examine the association between apolipoprotein E (APOE) polymorphisms and age-related macular degeneration (AMD) in a Chinese population. METHODS: The study consisted of 712 subjects, including 201 controls, 363 cases with early AMD, and 148 cases with exudative AMD. Genomic DNA was extracted from venous blood leukocytes. Common allelic variants of APOE (ε2, ε3, and ε4) were analyzed by PCR and direct...
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