Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of apolipoprotein E (rs7412 and rs429358) in age-related macular degeneration.

Ophthalmic genetics - 1 Aug 2018

Liutkeviciene Rasa, Vilkeviciute Alvita, Smalinskiene Alina, Tamosiunas Abdonas, Petkeviciene Janina, Zaliuniene Dalia, Lesauskaite Vaiva

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is the most common cause of incurable visual impairment in the developed countries. The main pathological change in AMD is the formation of drusen containing 40% of lipids, dominated by esterified cholesterol (EC) and phosphatidylcholine (PC), and protein. Haplotype ε4 of apolipoprotein E (ApoE) acts as a ligand for the low-density lipoprotein receptor and is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Gene Frequency

Share to Genotyping Techniques

Share to Macular Degeneration

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 29851526
DOI: 10.1080/13816810.2018.1479429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of apolipoprotein E (rs7412 and rs429358) in age-related macular degeneration.PMID 29851526Read ↗

Association of Apolipoprotein E Polymorphisms with Age-related Macular Degeneration Subtypes: An Updated Systematic Review and Meta-analysis.Semantic proximity Read ↗

Apolipoprotein E gene and age-related macular degeneration in a Chinese population.Semantic proximity Read ↗

Evaluation of APOE polymorphisms and the risk for age-related macular degeneration in a Southeastern Brazilian population.Semantic proximity Read ↗

Association of the apolipoprotein E gene with age-related macular degeneration: possible effect modification by family history, age, and gender.Semantic proximity Read ↗

Apolipoprotein E Isoforms and AMD.Semantic proximity Read ↗

Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies.Semantic proximity Read ↗

The epsilon4 allele of the apolipoprotein E gene as a potential protective factor for exudative age-related macular degeneration.Semantic proximity Read ↗

Associations of cholesteryl ester transfer protein (CETP) gene variants with predisposition to age-related macular degeneration.Semantic proximity Read ↗

Associations of Alzheimer Disease-Protective APOE Variants With Age-Related Macular Degeneration.Semantic proximity Read ↗

Genetic association of apolipoprotein E with age-related macular degeneration.Semantic proximity Read ↗

Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older PeopleSemantic proximity Read ↗

Interactions between Apolipoprotein E Metabolism and Retinal Inflammation in Age-Related Macular DegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.