CETP/LPL/LIPC gene polymorphisms and susceptibility to age-related macular degeneration.

doi:10.1038/srep15711

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Article

CETP/LPL/LIPC gene polymorphisms and susceptibility to age-related macular degeneration.

Scientific reports - 27 Oct 2015

Wang Ya-Feng, Han Yue, Zhang Rui, Qin Li, Wang Ming-Xu, Ma Le

Abstract excerpt

Three high-density lipoprotein (HDL)-related loci have been reported to be associated with age-related macular degeneration (AMD), but the results were inconsistent. In this study, the cholesteryl ester transfer protein (CETP) rs3764261 variant was significantly associated with an increased risk of AMD (odds ratio [OR] = 1.13, 95% confidence interval [CI]: 1.05-1.21, P < 0.001), and the hepatic lipase (LIPC)...

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Identifiers

PMID: 26503844
DOI: 10.1038/srep15711
PMCID: PMC4621603

Genes

CETP
LPL
LIPC
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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