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Increased herpes zoster risk associated with poor HLA-A immediate early 62 protein (IE62) affinity.

Immunogenetics - 1 Jun 2018

Meysman Pieter, De Neuter Nicolas, Bartholomeus Esther, Elias George, Van den Bergh Johan, Emonds Marie-Paule, Haasnoot Geert W, Heynderickx Steven, Wens Johan, Michels Nele R, Lambert Julien, Lion Eva, Claas Frans H J, Goossens Herman, Smits Evelien, Van Damme Pierre, Van Tendeloo Viggo, Beutels Philippe, Suls Arvid, Mortier Geert, Laukens Kris, Ogunjimi Benson

Abstract excerpt

Around 30% of individuals will develop herpes zoster (HZ), caused by the varicella zoster virus (VZV), during their life. While several risk factors for HZ, such as immunosuppressive therapy, are well known, the genetic and molecular components that determine the risk of otherwise healthy individuals to develop HZ are still poorly understood. We created a computational model for the Human Leukocyte Antigen...

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PMID: 29196796
DOI: 10.1007/s00251-017-1047-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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