Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

gE mutations and VZV genotypes jointly predict pain relief outcomes in herpes zoster: an integrative immunologic and modeling study.

Frontiers in immunology - 1 Jan 2026

Shi Ying, Li Bin, Li Nan, Su Ai, Tang Min

Abstract excerpt

Introduction: Herpes zoster (HZ), caused by reactivation of varicella-zoster virus (VZV), is associated with significant pain burden and risk of postherpetic neuralgia (PHN). However, early prediction of pain outcomes remains limited due to insufficient integration of viral genotypic features and host immune responses. This study aimed to investigate the distribution of VZV genotypes, characterize glycoprotein E...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Antibodies, Viral
Share to CD4 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Herpes Zoster

Share to Herpesvirus 3, Human

Share to Mutation

Share to Viral Envelope Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 42136640
DOI: 10.3389/fimmu.2026.1715267
PMCID: PMC13168172

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

gE mutations and VZV genotypes jointly predict pain relief outcomes in herpes zoster: an integrative immunologic and modeling study.PMID 42136640Read ↗

Unraveling the Immune Signature of Herpes Zoster: Insights Into the Pathophysiology and Human Leukocyte Antigen Risk Profile.Semantic proximity Read ↗

Epidemiology and clinical profile of herpes zoster in the varicella vaccine era: A case series studySemantic proximity Read ↗

Unraveling the immune signature of herpes zoster: Insights into pathophysiology and the HLA risk profileSemantic proximity Read ↗

Analysis of the genotyping of circulating strains and characteristics of Glycoprotein E of Varicella-Zoster Virus in Shanxi Province, China.Semantic proximity Read ↗

Varicella-zoster virus-derived major histocompatibility complex class I-restricted peptide affinity is a determining factor in the HLA risk profile for the development of postherpetic neuralgia.Semantic proximity Read ↗

Unraveling Interconnected Dynamics: Herpes Zoster, Postherpetic Neuralgia, and COVID-19 – A Bidirectional Mendelian Randomization AnalysisSemantic proximity Read ↗

[Genotypic diversity of the varicella-zoster virus (Herpesviridae: Varicellovirus) and human gene variants as risk factors for severe disease].Semantic proximity Read ↗

Causal Impact of Immune Phenotypes on Herpes Zoster and Postherpetic Neuralgia: Insights from Mendelian Randomization AnalysisSemantic proximity Read ↗

Analysis of clinical characteristics of central nervous system varicella-zoster virus infection: A Single-Center Cases Series StudySemantic proximity Read ↗

Increased herpes zoster risk associated with poor HLA-A immediate early 62 protein (IE62) affinity.Semantic proximity Read ↗

Exploring the causal role of the immune response to varicella-zoster virus on multiple traits: a phenome-wide Mendelian randomization study.Semantic proximity Read ↗

[The genotyping and molecular evolution of varicella-zoster virus].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.