Article
Rapid screening of rpoB and katG mutations in Mycobacterium tuberculosis isolates by high-resolution melting curve analysis.
Indian journal of medical microbiology - 1 Jan 2000
Haeili M, Fooladi A I, Bostanabad S Z, Sarokhalil D D, Siavoshi F, Feizabadi M M
Abstract excerpt
BACKGROUND: Early detection of multidrug-resistant tuberculosis (MDR-TB) is essential to prevent its transmission in the community and initiate effective anti-TB treatment regimen. MATERIALS AND METHODS: High-resolution melting curve (HRM) analysis was evaluated for rapid detection of resistance conferring mutations in rpoB and katG genes. We screened 95 Mycobacterium tuberculosis clinical isolates including 20...
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