Article
Detection of Isoniazid and Rifampin Resistance in Mycobacterium tuberculosis Clinical Isolates from Sputum Samples by High-Resolution Melting Analysis.
Current microbiology - 19 Jul 2022
Parsa Shadi, Yaghoubi Atieh, Izadi Nafiseh, Sabet Faezeh, Nik Leila Babaei, Derakhshan Mohammad, Rezaee Seyed Abdolrahim, Meshkat Zahra, Hoseini Seyed Javad, Jmehdar Saeid Amel, Kiani Fatemeh, Samiei Amin, Soleimanpour Saman
Abstract excerpt
The effective management of multidrug-resistant tuberculosis (MDR-TB) and the need for rapid and accurate screening of rifampin (RIF) and isoniazid (INH)-resistant Mycobacterium tuberculosis (Mtb) isolates are the most fundamental and difficult challenges facing the global TB control. The present study aimed to compare the diagnostic accuracy of high-resolution melting-curve analysis (HRMA) in comparison to...
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