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Article

Multiplex real-time PCR melting curve assay to detect drug-resistant mutations of Mycobacterium tuberculosis.

Journal of clinical microbiology - 1 Sept 2011

Luo Tao, Jiang Lili, Sun Weiming, Fu G, Mei Jian, Gao Qian

Abstract excerpt

Early diagnosis of drug-resistant Mycobacterium tuberculosis is urgently needed to optimize treatment regimens and to prevent the transmission of resistant strains. Real-time PCR assays have been developed to detect drug resistance rapidly, but none of them have been widely applied due to their complexity, high cost, or requirement for advanced instruments. In this study, we developed a real-time PCR method based...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21752982
DOI: 10.1128/JCM.02046-10
PMCID: PMC3165625

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