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Article

GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo.

Bioscience reports - 12 Dec 2014

Zang Shengbing, Lin Ting-Yu, Chen Xinji, Gencheva Marieta, Newo Alain N S, Yang Lixin, Rossi Daniel, Hu Jianda, Lin Shwu-Bin, Huang Aimin, Lin Ren-Jang

Abstract excerpt

Human GPKOW [G-patch (glycine-rich) domain and KOW (Kyrpides, Ouzounis and Woese) domain] protein contains a G-patch domain and two KOW domains, and is a homologue of Arabidopsis MOS2 and Saccharomyces Spp2 protein. GPKOW is found in the human spliceosome, but its role in pre-mRNA splicing remain...

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Source

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Identifiers

PMID: 25296192
DOI: 10.1042/BSR20140142
PMCID: PMC4266926

Genes

GPKOW
DHX16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25296192-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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