Article
Regulation of sex-specific RNA splicing at the Drosophila doublesex gene: cis-acting mutations in exon sequences alter sex-specific RNA splicing patterns.
Genes & development - 1 Jan 1990
Nagoshi R N, Baker B S
Abstract excerpt
Sex-specific alternative RNA splicing of the doublesex (dsx) pre-mRNA results in sex-specific polypeptides that regulate both male and female somatic sexual differentiation in Drosophila melanogaster. We have molecularly characterized a class of dsx mutations that act in cis to disrupt the regula...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA Transposable Elements
- Drosophila melanogaster
- Exons
- Female
- Genes
- Male
- Molecular Sequence Data
- Mutation
- Phenotype
- RNA Splicing
- Regulatory Sequences, Nucleic Acid
- Sex Determination Analysis