Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Smad3 transgenic reporter reveals TGF-beta control of zebrafish spinal cord development.

Developmental biology - 1 Dec 2014

Casari Alessandro, Schiavone Marco, Facchinello Nicola, Vettori Andrea, Meyer Dirk, Tiso Natascia, Moro Enrico, Argenton Francesco

Abstract excerpt

TGF-beta (TGFβ) family mediated Smad signaling is involved in mesoderm and endoderm specifications, left-right asymmetry formation and neural tube development. The TGFβ1/2/3 and Activin/Nodal signal transduction cascades culminate with activation of SMAD2 and/or SMAD3 transcription factors and their overactivation are involved in different pathologies with an inflammatory and/or uncontrolled cell proliferation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Activin Receptors, Type I
Share to Receptor, Transforming Growth Factor-beta Type I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Transforming Growth Factor beta

Share to Smad3 Protein

Share to Spinal Cord

Share to Transforming Growth Factor beta

Share to Transgenes

Share to Zebrafish Proteins

Source

Identifiers

PMID: 25286120
DOI: 10.1016/j.ydbio.2014.09.025

Genes

SMAD2
SMAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Smad3 transgenic reporter reveals TGF-beta control of zebrafish spinal cord development.PMID 25286120Read ↗

The TGFβ intracellular effector Smad3 regulates neuronal differentiation and cell fate specification in the developing spinal cordSemantic proximity Read ↗

Regulatory analysis of the mouse Fgf3 gene: control of embryonic expression patterns and dependence upon sonic hedgehog (Shh) signalling.Semantic proximity Read ↗

Transcriptional regulation by Pax3 and TGFbeta2 signaling: a potential gene regulatory network in neural crest development.Semantic proximity Read ↗

Unique and redundant roles of Smad3 in TGF-beta-mediated regulation of long bone development in organ culture.Semantic proximity Read ↗

Cerebellar Deficits and Hyperactivity in Mice Lacking Smad4Semantic proximity Read ↗

Smad1 and Smad8 function similarly in mammalian central nervous system development.Semantic proximity Read ↗

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling.Semantic proximity Read ↗

Retinal regeneration in adult zebrafish requires regulation of TGFβ signaling.Semantic proximity Read ↗

Analysis of neurogenesis using transgenic mice expressing GFP with nestin gene regulatory regions.Semantic proximity Read ↗

Canonical TGF-β Signaling Negatively Regulates Neuronal Morphogenesis through TGIF/Smad Complex-Mediated CRMP2 Suppression.Semantic proximity Read ↗

A transgenic neuroanatomical marker identifies cranial neural crest deficiencies associated with the Pax3 mutant Splotch.Semantic proximity Read ↗

HNF-3 beta as a regulator of floor plate development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.