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Article

HNF-3 beta as a regulator of floor plate development.

Cell - 14 Jan 1994

Sasaki H, Hogan B L

Abstract excerpt

The transcription factor gene HNF-3 beta is expressed in the ventral midline of the mouse embryonic neural tube, including the floor plate, a structure important for dorsoventral patterning and axonal guidance. To assess HNF-3 beta function, the gene has been ectopically expressed in the midbrain/hindbrain of transgenic embryos using an En-2 promoter/enhancer. By 18.5 days postcoitum, transgenic brains show a...

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PMID: 8287471
DOI: 10.1016/0092-8674(94)90176-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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