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Article

The melanocortin 1 receptor (Mc1r) variants do not account for the co-occurrence of Parkinson's disease and malignant melanoma.

Journal of molecular neuroscience : MN - 1 Dec 2014

Elincx-Benizri Sandra, Inzelberg Rivka, Greenbaum Lior, Cohen Oren S, Yahalom Gilad, Laitman Yael, Djaldetti Ruth, Orlev Yael, Scope Alon, Azizi Esther, Friedman Eitan, Hassin-Baer Sharon

Abstract excerpt

Parkinson's disease (PD) is characterized by loss of melanin-positive dopaminergic neurons in the substantia nigra. Malignant melanoma (MM), a melanocyte-derived neoplasm, occurs with higher than expected frequency among PD patients. Red-haired individuals exhibit a threefold risk for developing MM than dark-haired people; PD risk also increases with lighter hair color. One plausible explanation for the...

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PMID: 25284244
DOI: 10.1007/s12031-014-0425-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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