Article
Genetic analysis of MC1R variants in Chinese Han patients with sporadic Parkinson's disease.
Neuroscience letters - 12 Jan 2016
He Sihan, Tan Ting, Song Zhi, Yuan Lamei, Deng Xiong, Ni Bin, Chen Yong, Deng Hao
Abstract excerpt
Parkinson's disease (PD, OMIM 168600) is a neurodegenerative disorder featured by degeneration of melanin-positive dopaminergic neurons. Epidemiologic studies have suggested that PD and malignant melanoma (MM) might share common genetic components. Recently, the p.R160W variant in the melanocortin 1 receptor gene (MC1R, OMIM 155555), a risk factor for MM, has been identified to be associated with PD in Spanish...
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