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Article

The MC1R melanoma risk variant p.R160W is associated with Parkinson disease.

Annals of neurology - 1 May 2015

Tell-Marti Gemma, Puig-Butille Joan Anton, Potrony Miriam, Badenas Celia, Milà Montserrat, Malvehy Josep, Martí María José, Ezquerra Mario, Fernández-Santiago Rubén, Puig Susana

Abstract excerpt

Epidemiological studies have reported the co-occurrence of Parkinson disease (PD) and melanoma. Common genetic variants in the MC1R (melanocortin 1 receptor) gene, which determines skin and hair color, are associated with melanoma. Here we investigated whether genetic variants in MC1R modulate the risk of PD by sequencing the entire gene in 870 PD patients and 736 controls ascertained from Spain. We found that...

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Identifiers

PMID: 25631192
DOI: 10.1002/ana.24373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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