Article
The MUC5B promoter polymorphism is associated with idiopathic pulmonary fibrosis in a Mexican cohort but is rare among Asian ancestries.
Chest - 1 Feb 2015
Peljto Anna L, Selman Moises, Kim Dong Soon, Murphy Elissa, Tucker Laura, Pardo Annie, Lee Jung Su, Ji Wonjun, Schwarz Marvin I, Yang Ivana V, Schwartz David A, Fingerlin Tasha E
Abstract excerpt
BACKGROUND: Polymorphisms in the MUC5B promoter, TOLLIP, and nine additional genetic loci have been associated with idiopathic pulmonary fibrosis (IPF) within non-Hispanic white populations. It is unknown whether these variants account for risk of IPF in other racial/ethnic populations. We conducted a candidate single nucleotide polymorphism (SNP) association study in cohorts of Mexican and Korean patients with...
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