Article
MUC5B promoter polymorphism in Japanese patients with idiopathic pulmonary fibrosis.
Respirology (Carlton, Vic.) - 1 Apr 2015
Horimasu Yasushi, Ohshimo Shinichiro, Bonella Francesco, Tanaka Sonosuke, Ishikawa Nobuhisa, Hattori Noboru, Kohno Nobuoki, Guzman Josune, Costabel Ulrich
Abstract excerpt
BACKGROUND AND OBJECTIVE: A single nucleotide polymorphism (SNP) rs35705950 in the promoter of Mucin 5B (MUC5B) has been reported to be associated with idiopathic pulmonary fibrosis (IPF) mainly in Caucasian populations. This study was conducted to confirm the association between rs35705950 and IPF in a Japanese population. METHODS: Genomic DNA was extracted from blood samples in 384 Japanese and 137 German...
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