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Article

Potential clinical utility of MUC5B und TOLLIP single nucleotide polymorphisms (SNPs) in the management of patients with IPF.

Orphanet journal of rare diseases - 27 Feb 2021

Bonella Francesco, Campo Ilaria, Zorzetto Michele, Boerner Eda, Ohshimo Shinichiro, Theegarten Dirk, Taube Christian, Costabel Ulrich

Abstract excerpt

BACKGROUND: Genetic variants of TOLLIP and MUC5B, both on chromosome 11, have been reported to be associated with the development and/or prognosis of idiopathic pulmonary fibrosis (IPF). This retrospective study was conducted to investigate the association of MUC5B and TOLLIP SNPs with disease outcome in IPF. 62 IPF patients and 50 healthy controls (HC) from our Institution were genotyped for SNPs within MUC5B...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33639995
DOI: 10.1186/s13023-021-01750-3
PMCID: PMC7913255

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