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Article

Effects of MDM2 promoter polymorphisms on the development of cervical neoplasia in a Southeastern Brazilian population.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Dec 2014

Vargas-Torres Sandra Liliana, Portari Elyzabeth Avvad, Klumb Evandro Mendes, Guillobel Heloisa Carneiro da Rocha, Camargo Maria José de, Russomano Fábio Bastos, Macedo Jacyara Maria Brito

Abstract excerpt

We investigated the importance of two adjacent functional polymorphisms in the Murine Double Minute 2 (MDM2) gene, SNP285 G > C and SNP309 T > G, for the development of cervical lesions in a Southeastern Brazilian population (293 cases and 184 controls). MDM2 genotyping was performed by PCR-RFLP (Polymerase Chain Reaction-Restriction Fragment Length Polymorphism) and/or DNA sequencing. MDM2 SNP309 has potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins c-mdm2

Share to Uterine Cervical Neoplasms

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Source

Identifiers

PMID: 25271042
DOI: 10.3109/1354750X.2014.962614

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of MDM2 promoter polymorphisms on the development of cervical neoplasia in a Southeastern Brazilian population.PMID 25271042Read ↗

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