Article
Association between MDM2 SNP309 polymorphism and endometrial cancer risk in Polish women.
Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Dec 2012
Zając Agnieszka, Stachowiak Grzegorz, Pertyński Tomasz, Romanowicz Hanna, Wilczyński Jacek, Smolarz Beata
Abstract excerpt
The prognostic value of the MDM2 gene amplification/expression in many types of cancer remains unclear. Polymorphisms in the promoter region of the MDM2 gene have been shown to alter the protein expression and thus, may play a role in carcinogenesis. The aim of the present study was to evaluate the association between the risk of endometrial cancer and SNP309 polymorphisms in the MDM2 gene. The genotype analysis...
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