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Article

Murine double-minute 2 homolog single nucleotide polymorphism 309 and the risk of gynecologic cancer.

Human cell - 1 May 2009

Ueda Masatsugu, Yamamoto Michiko, Nunobiki Osamu, Toji Eisaku, Sato Naomi, Izuma Shinji, Okamoto Yoshiaki, Torii Kiyo, Noda Sadamu

Abstract excerpt

A functional T to G germline polymorphism in the promoter region of murine double-minute 2 homolog single nucleotide polymorphism 309 (MDM2-SNP309) has been reported to profoundly accelerate tumor formation, suggesting that it may also represent a powerful cancer predisposing allele. In this study, MDM2-SNP309 was examined in a total of 400 blood samples from 108 normal, 88 cervical, 119 endometrial and 85...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genital Neoplasms, Female

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Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins c-mdm2

Source

Identifiers

PMID: 19379464
DOI: 10.1111/j.1749-0774.2009.00068.x

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Murine double-minute 2 homolog single nucleotide polymorphism 309 and the risk of gynecologic cancer.PMID 19379464Read ↗

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