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Article

No association between SNP309 promoter polymorphism in the MDM2 and cervical cancer in a study from northeastern Brazil.

Cancer detection and prevention - 1 Jan 2007

Meissner Rosely de Vasconcellos, Barbosa Rodrigo Niskier Ferreira, Fernandes José Veríssimo, Galvão Tatiana Medeiros, Galvão Ana Flávia Oliveira, Oliveira Gustavo Henrique de Medeiros

Abstract excerpt

BACKGROUND: A functional variant in the MDM2 promoter (a T/G substitution, SNP309) was found to be associated with increased expression of MDM2 gene products and at significantly earlier age onset of tumors in both hereditary Li-Fraumeni individuals and sporadic cancer patients. We tested the hypothesis that this functional variant was associated with either risk or early age diagnosis of cervical cancer in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18023538
DOI: 10.1016/j.cdp.2007.09.001

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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No association between SNP309 promoter polymorphism in the MDM2 and cervical cancer in a study from northeastern Brazil.PMID 18023538Read ↗

The MDM2 promoter polymorphism SNP309T-->G and the risk of uterine leiomyosarcoma, colorectal cancer, and squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Effects of MDM2 promoter polymorphisms on the development of cervical neoplasia in a Southeastern Brazilian population.Semantic proximity Read ↗

MDM2 SNP309 does not confer an increased risk to oral squamous cell carcinoma but may modulate the age of disease onset.Semantic proximity Read ↗

MDM2 SNP309 G allele decreases risk but does not affect onset age or survival of Chinese leukaemia patients.Semantic proximity Read ↗

MDM2 SNP309 variation increases cervical cancer risk among Asians.Semantic proximity Read ↗

Association between a functional single nucleotide polymorphism in the MDM2 gene and sporadic endometrial cancer risk.Semantic proximity Read ↗

MDM2SNP309 does not associate with elevated MDM2 protein expression or breast cancer risk.Semantic proximity Read ↗

Results based on 124 cases of breast cancer and 97 controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer.Semantic proximity Read ↗

Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status.Semantic proximity Read ↗

Role of the MDM2 SNP309 polymorphism in the initiation and early age of onset of nasopharyngeal carcinoma.Semantic proximity Read ↗

Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population.Semantic proximity Read ↗

Lack of association between the MDM2-SNP309 polymorphism and breast cancer risk.Semantic proximity Read ↗

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