Article
Common variant on MDM2 contributes to endometrial cancer susceptibility: evidence based on 7 studies.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2014
Zhao Yan, Yang Xiaoer, Hao Xiaojiao, Pan Xiaolin, Zhao Bo, Ma Jingwen, Fang Jian, Zhao Minghong
Abstract excerpt
Due to its important biological function as a key negative regulator of p53, the mouse double minute 2 homologue (MDM2) gene has been extensively studied. A functional variant in the MDM2 gene promoter, single-nucleotide polymorphism 309 (SNP309) T > G (rs2279744), has been reported to cause an i...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
