Article
Leveraging hierarchical population structure in discrete association studies.
PloS one - 4 Jul 2007
Carlson Jonathan, Kadie Carl, Mallal Simon, Heckerman David
Abstract excerpt
Population structure can confound the identification of correlations in biological data. Such confounding has been recognized in multiple biological disciplines, resulting in a disparate collection of proposed solutions. We examine several methods that correct for confounding on discrete data with hierarchical population structure and identify two distinct confounding processes, which we call coevolution and...
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