Article
Roles of FGF-2 and TGF-beta/FGF-2 on differentiation of human mesenchymal stem cells towards nucleus pulposus-like phenotype.
Growth factors (Chur, Switzerland) - 1 Feb 2015
Zhou Xiaopeng, Tao Yiqing, Wang Jin, Liang Chengzhen, Wang Jun, Li Hao, Chen Qixin
Abstract excerpt
Human mesenchymal stem cells (MSCs) are reported to have the capability of differentiating towards nucleus pulposus (NP)-like phenotype under specific culture conditions. So far, the effects of fibroblast growth factor (FGF)-2 and the cocktail effects of transforming growth factor (TGF)-beta and FGF-2 on MSCs remain unclear. Therefore, we designed this study to clarify these effects. MSCs were cultured in...
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