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In Vitro Study on Interaction Between Human Nucleus Pulposus Cells and Mesenchymal Stem Cells Through Paracrine Stimulation

1 Aug 2008

Abstract excerpt

STUDY DESIGN: Coculture of human nucleus pulposus (NP) cells and mesenchymal stem cells (MSCs) using a noncontact system. OBJECTIVE: To investigate the interaction between NP cells and MSCs through paracrine stimulation. SUMMARY OF BACKGROUND DATA: Cell-based therapies have a potential role in the treatment of intervertebral disc degeneration. Upregulating the viability of NP cells and differentiating MSCs into...

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PMID: 18708927
DOI: 10.1097/brs.0b013e31817e6974

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