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Article

Differentiation of immortalized human precartilaginous stem cells into nucleus pulposus-like cells.

International journal of clinical and experimental pathology - 1 Jan 2015

Wang Qiong, Gu Xiaofeng, Cheng Li, Wang Junfang

Abstract excerpt

OBJECTIVE: We aimed to explore the differentiation of immortalized human precartilaginous stem cells (IPSCs) into nucleus pulposus (NP)-like cells induced by transforming growth factor-β1 (TGF-β1) and examine its biological characteristics. METHODS: The IPSCs were seeded onto chitosan/glycerophosphate (C/GP) scaffolds and induced into NP-like cells by adding TGF-β1 under hypoxic conditions. The growth and...

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PMID: 26045789
PMCID: PMC4440098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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