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Article

Development of a two-step protocol for culture expansion of human annulus fibrosus cells with TGF-β1 and FGF-2

12 Jul 2016

Abstract excerpt

BACKGROUND: Different biologic approaches to treat disc regeneration, including growth factors (GFs) application, are currently under investigation. Human annulus fibrosus (hAF) repair or regeneration is one of the key elements for maintenance and restoration of nucleus pulposus function. However, so far there is no effective treatment for this purpose. The aim of the present study was to investigate the response...

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PMID: 27405858
DOI: 10.1186/s13287-016-0332-1

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