Article
Fibroblast growth factor-2 maintains the differentiation potential of nucleus pulposus cells in vitro: implications for cell-based transplantation therapy.
Spine - 1 Mar 2007
Tsai Tsung-Ting, Guttapalli Asha, Oguz Erbil, Chen Lih-Huei, Vaccaro Alexander R, Albert Todd J, Shapiro Irving M, Risbud Makarand V
Abstract excerpt
STUDY DESIGN: To investigate effects of FGF-2 on nucleus pulposus cell growth and differentiation. OBJECTIVES: To elucidate the phenotypic changes that occur during expansion of nucleus pulposus cells in monolayer culture, and to investigate the effects of fibroblast growth factor (FGF)-2 on cell growth and differentiation. SUMMARY OF BACKGROUND DATA: Nucleus pulposus cells would have a limited application for...
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