Article
KRAS and BRAF mutational status in colon cancer from Albanian patients.
Diagnostic pathology - 30 Sept 2014
Martinetti Daniela, Costanzo Rosario, Kadare Shahin, Alimehmeti Mehdiu, Colarossi Cristina, Canzonieri Vincenzo, Berretta Massimiliano, Memeo Lorenzo
Abstract excerpt
BACKGROUND: Numerous clinical studies have shown that anti-EGFR therapies are effective only in a subset of patients with colorectal cancer. Mutations in the KRAS and BRAF genes have been confirmed as negative predictors of the response to EGFR-targeted therapies.In this study we evaluated KRAS and BRAF status in 159 colorectal cancer samples obtained from the University of Tirana. METHODS: We evaluated KRAS...
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