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Article

The AIB1 gene polyglutamine repeat length polymorphism contributes to risk of epithelial ovarian cancer risk: a case-control study.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2015

Han Guoping, Xie Song, Fang Hongming, Li Gang, Han Yinquan, Qin Zhen

Abstract excerpt

Genes coding for proteins involved in steroid hormone signaling have been identified as ovarian cancer risk-modifier candidates. AIB1 gene (amplified in breast cancer-1), an androgen receptor (AR) coactivator, expresses a polyglutamine (poly-Q) sequence within the carboxyl-terminal coding region. We hypothesized that genotypic variations in the androgen-signaling pathway promote aggressive epithelial ovarian...

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Identifiers

PMID: 25263716
DOI: 10.1007/s13277-014-2661-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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