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Article

AIB1 gene amplification and the instability of polyQ encoding sequence in breast cancer cell lines.

BMC cancer - 2 May 2006

Wong Lee-Jun C, Dai Pu, Lu Jyh-Feng, Lou Mary Ann, Clarke Robert, Nazarov Viktor

Abstract excerpt

BACKGROUND: The poly Q polymorphism in AIB1 (amplified in breast cancer) gene is usually assessed by fragment length analysis which does not reveal the actual sequence variation. The purpose of this study is to investigate the sequence variation of poly Q encoding region in breast cancer cell lines at single molecule level, and to determine if the sequence variation is related to AIB1 gene amplification. METHODS:...

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Identifiers

PMID: 16670003
DOI: 10.1186/1471-2407-6-111
PMCID: PMC1468420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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