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Article

The AIB1 gene polyglutamine repeat length polymorphism and the risk of breast cancer development.

Journal of cancer research and clinical oncology - 1 Feb 2011

Kleibl Zdenek, Havranek Ondrej, Kormunda Stanislav, Novotny Jan, Foretova Lenka, Machackova Eva, Soukupova Jana, Janatova Marketa, Tavandzis Spiros, Pohlreich Petr

Abstract excerpt

PURPOSE: Carriers of BRCA1/2 mutations are at high lifetime risk of breast cancer (BC); however, the BC onset broadly vary in individual patients. Recently, polyglutamine (poly-Q) repeat length polymorphism of the amplified in breast cancer 1 (AIB1) gene was analyzed as a risk factor influencing BC onset in BRCA1/2 mutation carriers with contradictory results. METHODS: We genotyped AIB1 poly-Q repeat in 243...

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Source

Identifiers

PMID: 20422428
DOI: 10.1007/s00432-010-0889-5

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The AIB1 gene polyglutamine repeat length polymorphism and the risk of breast cancer development.PMID 20422428Read ↗

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